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Human Tumor necrosis factor soluble receptor II (TNFsR-II) ELISA Kit

Cat no: KTE60216


Supplier: Abbkine Scientific Co.Ltd.
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TNFsR-II encodes a member of the TNF receptor superfamily of proteins. Tumor necrosis factor soluble receptor II is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.
Catalogue number: KTE60216
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P19438
Gene: 7132
Additional info: Human Tumor necrosis factor soluble receptor II (TNFsR-II) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNFRSF1A. No significant cross-reactivity or interference between Human TNFRSF1A and analogues was observed.

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