Human Tumor necrosis factor superfamily 15 (TNFSF15) ELISA Kit

VEGI is an anti-angiogenic protein. It belongs to tumor necrosis factor (ligand) superfamily, where it is member 15. The protein is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined.

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SPECIFICATIONS

Catalog Number

KTE60204

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

9966

Accession

O95150

Additional Info

Human Tumor necrosis factor superfamily 15 (TNFSF15) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNFSF15. No significant cross-reactivity or interference between Human TNFSF15 and analogues was observed.