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Human Twisted gastrulation protein homolog 1 (TWSG1) ELISA Kit

Human Twisted gastrulation protein homolog 1 (TWSG1) ELISA Kit

Cat no: KTE60114

Supplier: Abbkine Scientific Co.Ltd.
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The cDNA encodes a protein sharing 41% amino acid identity with Drosophila Tsg, 89% identity with the partial human Tsg sequence, and 94% identity with a mouse EST. The Tsg sequence contains a signal peptide, as expected for a secreted protein, and 2 conserved domains containing multiple cysteines at its amino and carboxy termini. At the late gastrula stage, maternal transcripts decrease and zygotic transcripts appear, specifically in the ventral region of the embryo. Tsg has ventralizing activity and is a bone morphogenetic protein (BMP) binding protein. The N-terminal domain of Tsg is sufficient to interact with BMP4 but not with chordin. Tsg competes for binding of BMP4 with the first cysteine-rich domain of chordin (CR1) but not with full-length chordin. Endogenous Tsg antagonizes CR1 activity.
Catalogue number: KTE60114
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q9GZX9
Gene: 57045
Additional info: Human Twisted gastrulation protein homolog 1 (TWSG1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TWSG1. No significant cross-reactivity or interference between Human TWSG1 and analogues was observed.

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