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Human TYRO protein tyrosine kinase-binding protein (TYROBP) ELISA Kit

Cat no: KTE60108


Supplier: Abbkine Scientific Co.Ltd.
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TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL.
Catalogue number: KTE60108
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O43914
Gene: 7305
Additional info: Human TYRO protein tyrosine kinase-binding protein (TYROBP) ELISA Kit has high sensitivity and excellent specificity for detection of Human TYROBP. No significant cross-reactivity or interference between Human TYROBP and analogues was observed.

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