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Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) ELISA Kit

Cat no: KTE61050

Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) ELISA Kit

is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

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SPECIFICATIONS

Catalog Number

KTE61050

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5777

Accession

P29350

Additional Info

Human Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTPN6. No significant cross-reactivity or interference between Human PTPN6 and analogues was observed.

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