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Human Ubiquitin B (UBB) ELISA Kit

Cat no: KTE60105

Human Ubiquitin B (UBB) ELISA Kit

Ubiquitin is a protein encoded by the UBB gene.one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.

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SPECIFICATIONS

Catalog Number

KTE60105

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

281370

Accession

P0CG53

Additional Info

Human Ubiquitin B (UBB) ELISA Kit has high sensitivity and excellent specificity for detection of Human UBB. No significant cross-reactivity or interference between Human UBB and analogues was observed.

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