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Human Uracil-DNA glycosylase (UNG) ELISA Kit

Human Uracil-DNA glycosylase (UNG) ELISA Kit

Cat no: KTE60087

Supplier: Abbkine Scientific Co.Ltd.
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UNG encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the nuclear (UNG2) and mitochondrial (UNG1) isoforms of UNG result from alternative splicing and the use of alternative promoters. The UNG1 and UNG2 proteins contain different N-terminal sequences, but the downstream 269 amino acids are common and include a short region that binds replication protein A and a larger, compact catalytic domain.
Catalogue number: KTE60087
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P13051
Gene: 7374
Additional info: Human Uracil-DNA glycosylase (UNG) ELISA Kit has high sensitivity and excellent specificity for detection of Human UNG. No significant cross-reactivity or interference between Human UNG and analogues was observed.

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