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Human Urocanate hydratase (UROC1) ELISA Kit

Cat no: KTE60083

Human Urocanate hydratase (UROC1) ELISA Kit

Catabolism of histidine begins with the conversion of histidine to urocanic acid by histidase (HAL). UROC1, or urocanase (EC 4.2.1.49), catalyzes the second step in histidine catabolism, the metabolism of urocanic acid to formiminoglutamic acid.\nEspinos et al. (2009) cloned human UROC1. The deduced protein contains a C-terminal catalytic domain with an evolutionarily conserved catalytic arginine (arg450). UROC1 had an apparent molecular mass of 74.8 kD by SDS-PAGE.Using a spectrophotometric assay, Espinos et al. (2009) demonstrated that purified recombinant UROC1 had robust urocanase activity.Espinos et al. (2009) determined that the UROC1 gene contains 20 exons.

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SPECIFICATIONS

Catalog Number

KTE60083

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

131669

Accession

Q96N76

Additional Info

Human Urocanate hydratase (UROC1) ELISA Kit has high sensitivity and excellent specificity for detection of Human UROC1. No significant cross-reactivity or interference between Human UROC1 and analogues was observed.

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