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Human USP6 N-terminal-like protein (USP6NL) ELISA Kit

Human USP6 N-terminal-like protein (USP6NL) ELISA Kit

Cat no: KTE60080

Supplier: Abbkine Scientific Co.Ltd.
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HAUSPis a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates.Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP acitivity generally stabilizes its substrate proteins. HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53. Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53. Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress.
Catalogue number: KTE60080
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q92738
Gene: 9712
Additional info: Human USP6 N-terminal-like protein (USP6NL) ELISA Kit has high sensitivity and excellent specificity for detection of Human USP6NL. No significant cross-reactivity or interference between Human USP6NL and analogues was observed.

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