Human Vascular Endothelial cell Growth Factor C (VEGF-C) ELISA Kit

VEGF-C has been shown to exhibit angiogenic and lymphangiogenic actions. The VEGF family of growth factors and receptors is involved in the development and growth of the vascular endothelial system. Two of its family members, VEGF-C and VEGF-D, regulate the lymphatic endothelial cells via their receptor VEGFR, thus acting as mitogens for these cells. VEGF-C expression is associated with hematological malignancies. Like VEGF it acts as survival factor on leukemia. Together with the expression of their receptors, VEGF and VEGF-C result in the generation of autocrine loops that may support cancer cell survival and proliferation. Further VEGF-C expression has been shown in gastrointestinal tract malignancies where it correlates with lymphatic invasion, lymphnode metastasis and reduced survival.

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SPECIFICATIONS

Catalog Number

KTE60058

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7424

Accession

P49767

Additional Info

Human Vascular Endothelial cell Growth Factor C (VEGF-C) ELISA Kit has high sensitivity and excellent specificity for detection of Human VEGFC. No significant cross-reactivity or interference between Human VEGFC and analogues was observed.