Human Vimentin (VIM) ELISA Kit

Vimentin is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all metazoan cells as well as bacteria. IF, along with tubulin-based microtubules and actin-based microfilaments, comprise the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion; vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition (EMT) during both normal development and metastatic progression. A vimentin monomer, like all other intermediate filaments, has a central ?-helical domain, capped on each end by non-helical amino (head) and carboxyl (tail) domains.

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SPECIFICATIONS

Catalog Number

KTE60054

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7431

Accession

P08670

Additional Info

Human Vimentin (VIM) ELISA Kit has high sensitivity and excellent specificity for detection of Human VIM. No significant cross-reactivity or interference between Human VIM and analogues was observed.