Human Vitamin K epoxide reductase complex subunit 1 (VKORC1) ELISA Kit

Cat no: KTE60051

Supplier: Abbkine Scientific Co.Ltd.

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Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. VKORC1 is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.

Catalogue number:	KTE60051
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	Q9BQB6
Gene:	79001
Additional info:	Human Vitamin K epoxide reductase complex subunit 1 (VKORC1) ELISA Kit has high sensitivity and excellent specificity for detection of Human VKORC1. No significant cross-reactivity or interference between Human VKORC1 and analogues was observed.

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Human Vitamin K epoxide reductase complex subunit 1 (VKORC1) ELISA Kit

Cat no: KTE60051

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