Hyaluronic Acid Binding Protein 1, Recombinant, Human (Hyaluronan Binding Protein 1, HABP1, C1qBP, C1q-R, Human Complement Component 1, q Subcomponent Binding Protein)

Human complement component 1, q subcomponent binding protein (C1QBP) is a ubiquitously expressed multifunctional phospho-protein that interacts with the globular heads of C1q (gC1q). This protein also interacts with a wide range of ligands and is implicated in cell signaling.\n\nMolecular Weight: \n23.9kD (210 aa)\n\nAA Sequence:\nMLHTDGDKAF VDFLSDEIKE ERKIQKHKTL PKMSGGWELE LNGTEAKLVR \nKVAGEKITVT FNINNSIPPT FDGEEEPSQG QKVEEQEPEL TSTPNFVVEV \nIKNDDGKKAL VLDCHYPEDE VGQEDEAESD IFSIREVSFQ STGESEWKDT \nNYTLNTDSLD WALYDHLMDF LADRGVDNTF ADELVELSTA LEHQEYITFL \nEDLKSFVKSQ\n\nApplications: \nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

H7980-36A

Size

100ug

Applications

ELISA

Form

Supplied as a liquid in 20mM Tris, pH 7.5, 1mM DTT, 20% glycerol.

Purity

(same/more than) 95% by SDS PAGE. Endotoxin: (same/less than)1.0EU/1ug (LAL)

References

1. Fogal, V., et al., Cancer Res. 68(17): 7210-7218 (2008). 2. Biswas, A.K., et al., PLoS Pathog. 3(9): 1271-1280 (2007). General References: 1. Thakur, S.C., et al., J. Androl. 27: 604 (2006). 2. Peerschke, E.I.B. & Ghebrehiwet, B., Immunobiology 212: 333 (2007). 3. Lynch, N.J., et al., FEBS Lett. 418: 111 (1997). 4. Jiang, J., et al., Proc. Natl. Acad. Sci. 96: 3572 (1999). 5. Rozanov, D.V., et al., J. Biol. Chem. 277: 9318 (2002). 6. Deb, T.B. & Datta, K., J. Biol. Chem. 271: 2206 (1996). 7. Lim, B.L., et al., J. Biol. Chem. 271: 26,739 (1996). 8. Grebrehiwet, B., et al., J. Exp. Med. 179: 1809 (1994). 9. Waggoner, S.N., et al., J. Leukoc. Biol. 82: epub (2007). 10. Innamorati, G., et al., Cell. Signal. 18: 761 (2006). 11. Robles-Flores, M., et al., J. Biol. Chem. 277: 5247 (2002). 12. Sunayama, J., et al., Cell Death Differ. 11: 771 (1994). 13. Pupo, A.S. & Minneman, K.P., J. Recept. Signal Transduct. 23(2-3): 185-195 (2003). 14. Schaerer, M.T., et al., J. Biol. Chem. 276: 26,597 (2001). 15. Peterson-Mahrt, S.K., et al., EMBO J. 18: 1014 (1999). 16. Chattopadhyay, C., et al., Nucleic Acids Res. 32: 3632 (2004). 17. Majumdar, M., et al., Biochem. Biophys. Res. Commun. 291(4): 829-837 (2002).

Alternative Names

p32, HABP1, gC1qR, GC1QBP, SF2p32