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Hydroxy Urea

Cat no: 014620


Supplier: United States Biological
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An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide. Form: Off-White Solid Melting Point: 133-136 degrees C Solubility: DMSO, Water
Catalogue number: 014620
Size: 10g
Form: Off-White Solid
Alternative names: N-Hydroxyurea; Biosupressin; Carbamohydroxamic Acid; Carbamoyl Oxime; Cytodrox; Droxia; HU; Hidrix; Hydrea; Hydreia; Hydroxycarbamide; Hydroxycarbamine; N-(Aminocarbonyl)hydroxylamine; Hydroxylurea; Hydura; Hydurea; Litaler; Litalir; N-Carbamoylhydroxylamine; NCI C04831; NSC 32065; Oxyurea; SK 22591; SQ 1089;
References: Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),

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