ICAD Antibody

Cat no: 250705

Supplier: ABBIOTEC

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Description
Additional Information

Inhibitor of CAD (ICAD, DNA fragmentation factor 45 kDa subunit, DFF-45 is an inhibitor of the caspase-activated DNase. Caspase-activated deo, Xenopus/Amphibian,yribonuclease (CAD) is also designated as DNA fragmentation factor 40 kDa subunit (DFF-40) and caspase-activated Dnase. CAD is a nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. ICAD is a heterodimer of DFFA and DFFB. Caspase-3 cleaves ICAD at 2 sites to generate an active factor.

Catalogue number:	250705
Reactivities:	Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	O00273
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse ICAD.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	ICAD; Inhibitor of Caspase-Activated Dnase; DNA fragmentation factor subunit alpha; DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; DFFA; DFF1; DFF45