ICSBP Antibody

Cat no: 252105

Supplier: ABBIOTEC

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Description
Additional Information

Interferon regulatory factor 8 (ICSBP) specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). ICSBP plays a negative regulatory role in cells of the immune system. ICSBP is ubiquitinated by TRIM21 in macrophages, a process that is strongly increased upon interferon gamma stimulation. This leads to the enhanced transcriptional activity of target cytokine genes.

Catalogue number:	252105
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	Q02556
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ICSBP.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Interferon regulatory factor 8; IRF-8; Interferon consensus sequence-binding protein; ICSBP; IRF8; ICSBP1