IFI16 Antibody

Cat no: 200210

Supplier: ABBIOTEC

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Description
Additional Information

Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC comple, Xenopus/Amphibian, after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.

Catalogue number:	200210
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	Q16666
Antigen:	Recombinant protein encompassing the PAAD domain (aa 6-102) of human IFI16.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Clonality:	ABT-1206
Additional info:	Gamma-interferon-inducible protein Ifi-16; Interferon-inducible myeloid differentiation transcriptional activator; IFI16; IFNGIP1