IFN-R1 (L461) pAb

Cat no: BS1754

Supplier: Bioworld Technology, Inc.

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The type I interferons, IFN-(alpha) and IFN-(beta), are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-(alpha) and IFN-(beta) appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-(gamma)) binds to a distinct receptor. This distinct receptor, IFN-(alpha)R, is only weakly responsive to type I interferons, in contrast to IFN-(alpha)/(beta)R, which binds to and responds effectively to IFN-(beta) and to several of the IFN-(alpha) subtypes. IFN-(alpha)/(beta)R is expressed as two alternatively spliced transcripts, designated IFN-(alpha)/(beta)R(alpha) (IFN-(alpha)/(beta)R1) and IFN-(alpha)/(beta)R(beta) (IFN- (alpha)/(beta)R2), both of which are involved in signal transduction and ligand binding.

Catalogue number:	BS1754
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunofluorescence, Immunohistochemistry
Size:	100ug/100ul
Swiss prot:	P17181
Dilutions:	IHC: 1:50~1:200 IF: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 410-460 of Human IFN-R1.
Species:	IFN-R1 (L461) pAb detects endogenous levels of Interferon alpha/beta receptor 1 protein.
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1; IFNAR; IFNR1; IFN R1; IFN-(alpha)/(beta)R(alpha);IFN-(alpha)/(beta)R1; IFN (alpha)/(beta)R(alpha); IFN(alpha)/(beta)R1; IFN(alpha)/(beta)-R(alpha);IFN(alpha)/(beta) R1;
Additional info:	For research use only, not for use in diagnostic procedure.

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IFN-R1 (L461) pAb

Cat no: BS1754

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