IFN-R1 (L461) Peptide

The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma ) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN- alpha/betaR2), both of which are involved in signal transduction and ligand binding.

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SPECIFICATIONS

Catalog Number

BS1754P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide IFN-R1 (L461). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P17181

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS1754 IFN-R1 (L461) pAb.

Alternative Names

Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1; IFNAR; IFNR1; IFN R1; IFN-alpha/betaRalpha;IFN-alpha/betaR1; IFN alpha/betaRalpha; IFNalpha/betaR1; IFNalpha/beta-Ralpha;IFNalpha/beta R1;