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Ifnl2, Recombinant, Human (Interferon lambda-2, IFN-lambda-2, Interleukin-28A, IL-28A, IL28A)

Cat no: 149704


Supplier: United States Biological
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IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant mouse IFN-lambda 2 is a 19.8kD protein containing 175aa. Source: Recombinant protein corresponding to mouse IFN-lambda 2, expressed in E.coli. Biological Activity: Determined by its ability to activate STAT following receptor-ligand interaction. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MDPVPRATRL PVEAKDCHIA QFKSLSPKEL QAFKKAKDAI EKRLLEKDMR CSSHLISRAW DLKQLQVQER PKALQAEVAL TLKVWENMTD SALATILGQP LHTLSHIHSQ LQTCTQLQAT AEPKPPSRRL SRWLHRLQEA QSKETPGCLE DSVTSNLFRL LTRDLKCVAS GDQCV Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 149704
Size: 5ug
Form: Supplied as a lyophilized powder.
Purity: ~98% (SDS-PAGE and HPLC)

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