IgA, Human

Human Immunoglobulin A (IgA) represents about 15% to 20% of immunoglobulins in the blood, although Human Immunoglobulin A (IgA)is primarily secreted across the mucosal tract into the stomach and intestines. This prevents microbes from binding to epithelial cells in the digestive and respiratory tracts. Human Immunoglobulin A (IgA)helps to fight against pathogens that contact the body surface, are ingested, or are inhaled. \n\nApplications: \nSuitable for use in ELISA, Western Blotting. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degrees C or colder. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

I1890-10B

Size

1mg

Applications

ELISA, IF, IHC, IP, WB

Form

Supplied as a liquid in PBS, pH 7.2.

Purity

(same/more than) 96% (SDS-PAGE)

References

Human Immunoglobulin A, Human IgA research:A comparison of the binding of secretory component to immunoglobulin A (IgA) in human colostral S-IgA1 and S-IgA2.Human Immunoglobulin A (IgA) REF: Immunology\nVolume 120 Issue 2 Page 273 - February 2007/Immunoglobulin\n\nHuman Immunoglobulin A (IgA) Research Article:Establishment of a 2-D human urinary proteomic map in IgA (Human Immunoglobulin A) (IgA)nephropathy. Human Immunoglobulin A (IgA)REF: PROTEOMICS Volume 6, Issue 3 , Pages 1066 - 1076/Immunoglobulin/human\n\nHuman Immunoglobulin A (Human IgA) study: Human intestinal Immunoglobulin A IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria.Human Immunoglobulin A (IgA) REF: Gastroenterology. 2005 Jun;128(7):1879-89/Immunoglobulin/human/iga.\n\nHuman Immunoglobulin A (Human IgA) research: Secretory immunoglobulin A (sIgA) deficiency in serum of patients with GALTectomy (appendectomy and tonsillectomy). Human Immunoglobulin A (Human IgA) ref:Clinical Immunology, April 2007/Immunoglobulin/human/iga\n\nHuman Immunoglobulin A (Human IgA) research: novel IgA-like immunoglobulin in the reptile Eublepharis macularius.Human Immunoglobulin A (Human IgA) ref:Developmental & Comparative Immunology, Volume 31, Issue 6, 2007, Pages 596-605/Immunoglobulin/human/iga\n\nHuman Immunoglobulin A (Human IgA) research: Utility in Clinical Practice of Immunoglobulin A Anti-Tissue Transglutaminase Antibody for the Diagnosis of Celiac Disease.Human Immunoglobulin A (Human IgA) ref:\nClinical Gastroenterology and Hepatology, Volume 4, Issue 6, June 2006, Pages 726-730/Immunoglobulin/human/iga\n\nHuman Immunoglobulin A (Human IgA) research: Stressful life events are associated with low secretion rates of immunoglobulin A in saliva in the middle aged and elderly.Human Immunoglobulin A (Human IgA) ref:\nBrain, Behavior, and Immunity, Volume 20, Issue 2, March 2006, Pages 191-197/Immunoglobulin/human/iga\n\nHuman Immunoglobulin A (Human IgA) research: comparative study of secretory immunoglobulin A IgA and immunoglobulin G in host defense in an in vitro pneumonia model.Human Immunoglobulin A (Human IgA) ref:\nThe American Journal of Surgery, Volume 191, Issue 3, March 2006, Pages 386-390/Immunoglobulin/human/iga\n\nHuman Immunoglobulin A (Human IgA) research: Secretory immunoglobulin A ,IgA in saliva of women with oral and genital HPV infection.Human Immunoglobulin A (Human IgA) ref: \nEuropean Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 124, Issue 2, 1 February 2006, Pages 227-231/Immunoglobulin/human/iga