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IkB beta CT, Control Peptide

Cat no: I2500-10

IkB beta CT, Control Peptide

NFkB exists in the cytoplasm as a complex with a 38kDa inhibitor protein, IkB (MAD-3). Activation of NFkB by different stimuli, including TNFa and PMA, requires the dissociation of the inhibitor protein. Dissociation is regulated by the phosphorylation of IkB on serine residues 32 and 36 which targets IkB for ubiquinitation and proteasome mediated degradation. The NFkB complex then translocates to the nucleus and activates transcription of responsive genes.\n\nAA Sequence: RQP PSP ASK PLP DDP NPA\n\nControl peptide should be used at 1mg per 1ml of antiserum in per assay. \n\nIntended for use as a control peptide when used with anti-IkB beta (C-terminal specific) to block specific interaction of anti-IkB beta (C-terminal specific) with the IkB beta subunit.

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SPECIFICATIONS

Catalog Number

I2500-10

Size

50ug

Form

Supplied as a lyophilized powder.

Purity

(same/more than) 80%

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