IL-1b is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses including the activation of B and T cells. Recombinant human IL-1b is a 17.0kD protein containing 153aa residues.
Source:
Recombinant corresponding to Human IL-1b expressed in E.coli.
Molecular Weight:
~17kD
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by murine C3H/HeJ thymocytes is ~0.1ng/ml, corresponding to a specific activity of ~1x10e7 units/mg.
Endotoxin:
~0.1ng/ug
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.