IL-1alpha (mouse) Matched Pair Detection Set (Interleukin-1alpha)

Supplier:

United States Biological

Cat no: 044907

IL-1alpha (mouse) Matched Pair Detection Set (Interleukin-1alpha)

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1alpha and IL-1beta. Although most activators fully rely on the inflammasome for IL-1alpha secretion, some induce the processing and secretion of IL-1alpha in an inflammasome-independent manner.\n\nStorage and Stability:\nShort-term Storage: -20 degrees C\nLong-term Storage: -20 degrees C\nStable for at least 1 year after receipt when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

044907

Size

1 Set

Additional Info

Detects mouse IL-1alpha. Does not detect human IL-1alpha or mouse IL-1beta.

Alternative Names

Interleukin-1alpha

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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Applications

ELISA, IHC, WB

Hosts

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Reactivities

Hum

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PI4K2A, NT (Phosphatidylinositol 4-kinase Type 2 alpha, PIK42A, Phosphatidylinositol 4-kinase Type II-alpha, PI4KII, DKFZp761G1923, RP11-548K23.6) (APC)

Applications

ELISA, IF, IHC, WB

Hosts

Rabbit

Reactivities

Hum

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PI 4 Kinase Type 2 beta, CT (Phosphatidylinositol 4-kinase Type 2 beta, PI4K2B, PIK42B, Phosphatidylinositol 4-kinase Type II-beta, PI4KII-beta, PI4KIIB, FLJ11105) (APC)

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

United States Biological

PI 4 Kinase Type 2 beta, NT (Phosphatidylinositol 4-kinase Type 2 beta, PI4K2B, PIK42B, Phosphatidylinositol 4-kinase Type II-beta, PI4KII-beta, PI4KIIB, FLJ11105) (APC)

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

United States Biological

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Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

United States Biological

PIM3, CT (Pim-3, Pim-3 Oncogene, Serine/threonine Protein Kinase Pim-3) (APC)

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

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PIP5K3 (Phosphatidylinositol-3-phosphate 5-kinase Type III, CFD, FAB1, FLJ37746, FYVE Finger-containing Phosphoinositide Kinase, KIAA0981, MGC40423, 1-phosphatidylinositol-3-phosphate 5-kinase, Phosphatidylinositol-3-phosphate 5-kinase, PIP5K, PIPkin-III,

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

United States Biological

PISD, ID (Phosphatidylserine Decarboxylase Proenzyme, Phosphatidylserine Decarboxylase alpha Chain, Phosphatidylserine Decarboxylase beta Chain) (APC)

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

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