IL-1RA BioAssay(TM) ELISA Kit, Human

Sandwich ELISA quantitative detection kit for Human IL-1RA in cell culture supernates, serum and plasma (heparin, EDTA).\n\nThe interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene.1.2The human IL1RN gene was localized to the long arm of chromosome 2 at band 2q14.2 by fluorescence in situ hybridization.3 IL-1RA is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses.4\n\nAssay Range:\n31.2pg/ml-2000pg/ml\n\nSensitivity:\n< 2 pg/ml\n\nCrossreactivity:\nThere is no detectable cross-reactivity with other relevant proteins.\n\nUniprot ID:\nP18510\n\nEntrez Gene ID:\n3557\n\nKit Components:\n96-well plate pre-coated with anti-IL-1RA, Human\nLyophilized recombinant IL-1RA, Human standard, 10ng/tube, 2Ea\nUSB Cat No Kit Component\n143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution)\n143697 Sample diluent buffer, 30ml\n143698 Antibody diluent buffer, 12ml\n143699 ABC diluent buffer, 12ml\n143700 TMB color developing agent, 10ml\n143701 TMB stop solution, 10ml\n\nStorage and Handling:\nStore at 4 degrees C for 6 months, at -20 degrees C for 12 months. Avoid multiple freeze-thaw cycles.

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SPECIFICATIONS

Catalog Number

143905

Size

96Tests

References

1. Steinkasserer A, Spurr NK, Cox S, Jeggo P, Sim RB (July 1992). \"The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci\". Genomics 13 (3): 654