IL-37, truncated, Recombinant, Human (His) (Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1)

IL-37 (IL-1F7; IL-1H4) belongs to the IL-1 family of proteins. It binds to the interleukin-18 receptor (IL-18R) but not to the IL-1 receptor. It plays an important role as a link between innate and adaptive immunity. IL-37 is a new player in inflammatory and immune responses, mediated by the IL-18/IL-18R axis. It was shown to inhibit tumor growth.\n\nSequence:\nHuman IL-37 (aa 46-218) is fused at the C-terminus to a His-tag.\n\nStorage and Stability:\nShort-term Storage: +4 degrees C\nLong-term Storage: -20 degrees C\nStable for at least 6 months after receipt when stored at -20 degrees C. Working aliquots are stable for up to 3 months when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

044946

Size

10ug

Form

Supplied as a lyophilized powder from a 0.2um-filtered solution in 50mM TRIS-Cl, pH 8.2, 150mM NaCl.

Purity

>95% (SDS-PAGE)

Alternative Names

Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1