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IL-3Rbeta Peptide

IL-3Rbeta Peptide

Cat no: BS60334P


Supplier: Bioworld Technology, Inc.
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Interleukin-3, or IL-3, is a pleiotropic cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL-3 exerts its biological effects through a receptor which consists of a ligand-specific alpha subunit (IL-3Ralpha) and a signal transducing beta subunit (IL-3Rbeta) common to the IL-3/IL-5/GM-CSF receptors. The alpha subunits are low-affinity ligand-binding proteins while the beta subunits do not themselves bind ligand, but are required for high affinity binding by the alpha subunits. The mouse IL-3 receptor has two distinct beta subunits, one that functions only in IL-3-mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine beta subunits are 91% homologous at the amino acid level but only 56% homologous to the human beta subunit.
Catalogue number: BS60334P
Applications: Block/Neutralize/Inhibit
Swiss prot: P32927
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide IL-3Rbeta. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Cytokine receptor common subunit beta; CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD131; CSF2RB; IL3RB; IL5RB; IL3Rbeta
Additional info: This peptide can be used with studies using BS60334 IL-3Rbeta pAb.

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