IL-4R(alpha) (G493) pAb

Cat no: BS2998

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.

Catalogue number:	BS2998
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Immunofluorescence, Western Blot
Size:	100ug/100ul
Swiss prot:	P24394
Dilutions:	WB: 1:500~1:1000 IF: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 460-510 of Human IL-4R(alpha).
Species:	IL-4R(alpha) (G493) pAb detects endogenous levels of IL-4R(alpha) protein.
Molecular weight:	~88 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	IL4R
Additional info:	For research use only, not for use in diagnostic procedure.

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IL-4R(alpha) (G493) pAb

Cat no: BS2998

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