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Il15, Recombinant, Rat (Interleukin-15, IL-15, Interleukin 15)

Cat no: 149720


Supplier: United States Biological
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IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5kD protein consisting of 115aa. Source: Recombinant protein corresponding to rat IL-15, expressed in E.coli. Biological Activity: Determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells. The ED50 was found to be <10ng/ml Specific Activity: >1x10e5units/mg Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MNWIDVRYDL EKIESLIQFI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VIESGCKECE ELEERNFTEF LQSFIHIVQM FINTS Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 149720
Size: 2ug
Form: Supplied as a lyophilized powder.
Purity: ~98% (SDS-PAGE and HPLC)

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