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IL17A, Recombinant, Human, Western Blot Control (Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated Antigen 8, CTLA-8, CTLA8, IL17)

Cat no: I8439-02F

IL17A, Recombinant, Human, Western Blot Control (Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated Antigen 8, CTLA-8, CTLA8, IL17)

nterleukin 17A (IL-17A) is the original member of the IL-17 family of structurally related cytokines (IL-17 A to IL-17F) that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17A is a pro-inflammatory cytokine produced primarily by T cells and is commonly associated with the allergic response facilitating the release of other cytokines, chemokines and prostaglandins from a variety of cell types. IL-17A exists in vitro as a homodimer of two 132aa chains.\n\nSource: \nRecombinant corresponding to aa24-155 from human IL-17A monomer coding sequence, fused to 6x His-tag at N-terminal, expressed in E. coli.\n\nApplications:\nSuitable for use in Western Blot as a control. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

I8439-02F

Size

10ug

Applications

WB

Form

Supplied as a liquid in 25mM Tris-HCl, pH6.8, 50mM DTT, 1% SDS, 0.1% Bromophenol Blue, 2.5% glycerol.

Purity

Purified (SDS-PAGE)

References

1. Gaffen S.L. et al., (2006) Vitam. Horm. 74: 255-282.

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