Home  >  Products  >  IL17E, Recombinant, Human (Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, UNQ3120/PRO10272)

IL17E, Recombinant, Human (Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, UNQ3120/PRO10272)

Cat no: 149633


Supplier: United States Biological
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IL-17E is a disulfide-linked homodimer of two 145aa polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NK-kB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8kD disulfide-linked homodimer of two 145aa polypeptide chains. Source: Recombinant protein corresponding to human IL-17E, expressed in E.coli. Biological Activity: Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100ng. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MYSHWPSCCP SKGQDTSEEL LRWSTVPVPP LEPARPNRHP ESCRASEDGP LNSRAISPWR YELDRDLNRL PQDLYHARCL CPHCVSLQTG SHMDPRGNSE LLYHNQTVFY RRPCHGEKGT HKGYCLERRL YRVSLACVCV RPRVMG Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 149633
Size: 5ug
Form: Supplied as a lyophilized powder.
Purity: ~98% (SDS-PAGE and HPLC)

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