IL28RA, CT (IL28RA, IFNLR1, LICR2, Interleukin-28 receptor subunit alpha, Cytokine receptor class-II member 12, Cytokine receptor family 2 member 12, Interferon lambda receptor 1, Likely interleukin or cytokine receptor 2) (PE)

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze R-Phycoerythrin conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

037006-PE

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to R-Phycoerythrin (R-PE).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)\nMagracheva, E., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 1), 61-63 (2010) :\nWitte, K., et al. Genes Immun. 10(8):702-714(2009)\nLaje, G., et al. Pharmacogenet. Genomics 19(9):666-674(2009)\nTrynka, G., et al. Gut 58(8):1078-1083(2009)

Additional Info

Human

Alternative Names

IL28RA, IFNLR1, LICR2, Interleukin-28 receptor subunit alpha, Cytokine receptor class-II member 12, Cytokine receptor family 2 member 12, Interferon lambda receptor 1, Likely interleukin or cytokine receptor 2