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Immunoglobulin Superfamily Member 3 (IGSF3, EWI-3) (PE)

Cat no: I7502-95B

Immunoglobulin Superfamily Member 3 (IGSF3, EWI-3) (PE)

IGSF3 (Immunoglobulin superfamily member 3; also known as EWI-3) is a member of the EWI subfamily of the Ig- superfamily of molecules. It is a type I transmembrane protein that likely exists as a homodimer in kidney and lung. The mature molecule is 1195aa in length, and contains an extended 1127aa extracellular domain (ECD; aa20-1146). There are seven ECD V-type Ig-like domains, the second of which exhibits a characteristic Glu-Trp-Ile motif. There are at least two potential splice variants. One shows a truncation after Pro833; a second shows a deletion of aa408-427. Over aa20-1125, human IGSF3 shares 92% aa identity with mouse IGSF3.\n\nApplications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: 10ul labels 1-2.5 x 10e5 cells\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nMouse myeloma cells with B cells from a mouse immunized with purified, NS0-derived human IGSF3 (aa20-1125).\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

I7502-95B

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

Additional Info

Recognizes human IGSF3. Species Crossreactivity: mouse (92%).

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