Immunoglobulin Superfamily Member 4C (IGSF4C, Nectin-Like 4, TSLC1-Like Protein 2, TSLL2)

Immunoglobulin Superfamily, member 4C (IGSF4C), also known as Nectin-like protein 4 (Necl-4), SynCAM4, or TSLL-2, is a type I transmembrane glycoprotein adhesion molecule. Expression at 55 kD in epithelia of kidney, bladder and prostate, 52kD in brain, and 50 or 48kD in the testes may be due to variable glycosylation. IGSF4C participates in Ca 2+ -independent, mainly homophilic cell-cell adhesion activity and is a proposed tumor suppressor. Human IGSF4C contains a 306 aa extracellular region with one V-type and two C2-type Ig-like domains. Human IGSF4C shares 98-99% amino acid identity with mouse, rat, dog and cow IGSF4C.\n\nApplications: \nSuitable for use in Western Blot and ELISA. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1-2ug/ml\nELISA: 0.5-1ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

I7502-70C

Size

100ug

Applications

ELISA, WB

Hosts

Rat

Reactivities

Hum

Form

Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

Additional Info

Recognizes human IGSF4C.