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IMP-3, Recombinant, Human (Insulin-like Growth Factor 2 mRNA Binding Protein 3, IGF2 mRNA-binding Protein 3, IGF2BP3, IMP3, IGF-II mRNA-binding Protein 3, CT98, KH Domain-containing Protein Overexpressed in Cancer, hKOC, KOC1, VICKZ Family Member 3, VICKZ

Cat no: 149546

IMP-3, Recombinant, Human (Insulin-like Growth Factor 2 mRNA Binding Protein 3, IGF2 mRNA-binding Protein 3, IGF2BP3, IMP3, IGF-II mRNA-binding Protein 3, CT98, KH Domain-containing Protein Overexpressed in Cancer, hKOC, KOC1, VICKZ Family Member 3, VICKZ

IMP-3, a member of the insulin-like growth factor-II (IGF-II) mRNA-binding protein (IMP) family, is expressed mainly during embryonic development and in some tumors. IMP-3 is considered to be an oncofetal protein.\n\nSource:\nRecombinant protein corresponding to human IMP-3, expressed in E. coli.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nAliquot to avoid repeated freezing and thawing and store at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

149546

Size

25ug

Applications

ELISA, WB

Form

Supplied as a liquid in 20mM Tris-HCl, 150mM sodium chloride, 1mM EDTA, 5mM glutathione, 0.5mM GSSH, 10% glycerol.

Purity

~90% (Nickel NTA Affinity Chromatography)

References

1. Liao (2005) The RNA-binding protein IMP-3 is a translational activator of insulin-like growth factor II leader-3 mRNA during proliferation of human K562 leukemia cells. J Biol Chem 280(18):18517-24.\n2. Goodenough UW (1993) Activation of adenylyl cyclase in Chlamydomonas reinhardtii by adhesion and by heat. J Cel Biol 122(1):137-47.

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