Importin beta-1 Antibody

Cat no: 252121

Supplier: ABBIOTEC

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Description
Additional Information

Importin subunit beta-1 (importin beta-1) functions in nuclear protein import, either in association with an adapter protein, such as an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, importin beta-1 functions as a NLS receptor. Docking of the importin/substrate comple, Xenopus/Amphibian, to the nuclear pore comple, Xenopus/Amphibian, (NPC) is mediated by importin beta-1 through binding to nucleoporin F, Xenopus/Amphibian,FG repeats and the comple, Xenopus/Amphibian, is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.

Catalogue number:	252121
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q14974
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human importin beta-1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Importin subunit beta-1; Karyopherin subunit beta-1; Nuclear factor p97; Pore targeting comple, Xenopus/Amphibian, 97 kDa subunit; PTAC97; Importin-90