INDO Peptide

Cat no: BS60456P

Supplier: Bioworld Technology, Inc.

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Indoleamine 2,3-dioxygenase (IDO) is an IFN-gamma inducible enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. The gene encoding human IDO maps to chromosome 8p12-p11. IDO, also known as INDO, is an important modulator of immunological responses and protects allogeneic concepti from alloreactive maternal lymphocytes. IDO mediates an interesting inhibitory effect of HeLa cells co-cultured with human PBLs. The ILN-2-induced proliferation response of PBLs is diminished in the presence of HeLa cells while an IDO inhbitor negates this effect. Flow cytometric analysis indicates both mature and immature CD123-positive dentritic cells suppress T cell activity using IDO. IDO-transfected cells co-cultured with T cells reduces T cell proliferation.

Catalogue number:	BS60456P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P14902
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide INDO. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	IDO 1; IDO; IDO-1; IDO1; INDO; Indole 2 3 dioxygenase; indoleamine 2 3 dioxygenase 1; indoleamine 2 3 dioxygenase; Indoleamine 2; 3-dioxygenase 1; Indoleamine pyrrole 2 3 dioxygenase; Indoleamine-pyrrole 2;
Additional info:	This peptide can be used with studies using BS60456 INDO pAb.

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INDO Peptide

Cat no: BS60456P

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