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Indolmycin (Antibiotic PA 155A)

Cat no: I0798


Supplier: United States Biological
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Indolmycin is a highly selective antibiotic which acts as a tryptophan anti-metabolite. Recent research has shown that indolmycin is active against Mycobacteria and Helicobacter pylori and can stimulate transcription in Escherichia coli. Purity: >99% by HPLC, mixture of diastereoisomers Solubility: Soluble in ethanol, methanol, DMF or DMSO. Related to: Pimprinine
Catalogue number: I0798
Size: 1mg
Purity: >99% by HPLC, mixture of diastereoisomers
Alternative names: Antibiotic PA 155A
References: 1. Indolmycin resistance of Streptomyces coelicolor A3(2) by induced expression of one of its two tryptophanyl-tRNA synthetases. Kitabatake M. et al. J. Biol. Chem. 2002, 277, 23882. 2. Development of a stereoselective practical synthetic route to indolmycin, a candidate anti-H. pylori agent. Hasuoka A. et al. Chem. Pharm. Bull. 2001, 49, 1604. 3. Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coli. Bogosian G. et al. J. Bacteriol. 1983, 153, 1120.

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