Insulin-like 3 Antibody

Cat no: 251865

Supplier: ABBIOTEC

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Description
Additional Information

Insulin-like 3 plays a role in testicular function. Insulin-like 3 is a trophic hormone with a role in testicular descent in fetal life. Insulin-like 3 is a ligand for LGR8 receptor. Insulin-like 3 is a heterodimer of a B chain and an A chain linked by two disulfide bonds. Defects in insulin-like 3 are a cause of cryptorchidism (CRYPTO), also known as impaired testicular descent. CRYPTO is one of the most frequent congenital abnormalities in humans, involving 2-5% of male births. CRYPTO is associated with increased risk of infertility and testicular cancer.

Catalogue number:	251865
Reactivities:	Human, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P51460
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human insulin-like 3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Insulin-like 3; Leydig insulin-like peptide; Ley-I-L; Rela, Xenopus/Amphibian,in-like factor; INSL3; RLF; RLNL