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Insulin-Like Growth Factor II, Recombinant, Human (Human IGF-II, IGF-II, IGFII, IGFII, IGF2, IGF-2, IGF 2)

Insulin-Like Growth Factor II, Recombinant, Human (Human IGF-II, IGF-II, IGFII, IGFII, IGF2, IGF-2, IGF 2)

Cat no: I7661-14A

Supplier: United States Biological
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Biological Activity: Receptor binding to the IGF-II receptor in L6 myoblasts: ED50 51.14 ng/ml, as determined by an independent laboratory. At 10ng/ml this material gave a 3.4 fold stimulation of 3 H thymidine incorporation over background in chick embryo ?broblasts. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degrees C or colder. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: I7661-14A
Size: 25ug
Form: Supplied as a lyophilized powder.
Purity: (same/more than) 95% by H.P.L.C.
Alternative names: Human IGF-II, IGF-II, IGFII, IGFII, IGF2, IGF-2, IGF 2, h-IGF-II, rh-IGF-II, recombinant human IGF-II, recombinant IGF-II, IGF
References: 1. Lowe, W.L., In: Insulin-Like Growth Factors: Molecular and Cellular Aspects LeRoith, D., CRC Press Inc. Boca Raton, p49, 1991. 2. LeRoith, D., and Roberts, Jr., CT. Ann. New York Acad. Sci. 692: 1, 1993. 3. Francis, G.L., et al., Novel recombinant fusion protein analogues of insulin-like growth-factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor binding for enhanced biological potency. J. Mol. Endocrinol. 8: 213

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