Specific for both rat and mouse insulin-proinsulin (different antigenic determinants), Kd 8.1 x 10-8 M. Cross-react with human, bovine and porcine insulin and proinsulin. Can be used: detection of rat-mouse insulin/proinsulin in two-site enzyme immunoassay, recommend pair (coating - conjugate): D6C4 - D3E7; for immunohistochemistry on frozen sections.