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IQGAP1, NT (IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195) (APC)

Cat no: 037089-APC

IQGAP1, NT (IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195) (APC)

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

037089-APC

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Hayashi, H., et al. Int. J. Cancer 126(11):2563-2574(2010)\nLiang, S., et al. Proteomics 10(7):1474-1483(2010)\nNakhaei-Nejad, M., et al. Eur. J. Immunol. 40(1):204-213(2010)\nWang, J.B., et al. J. Cell. Sci. 122 (PT 12), 2024-2033 (2009) :\nUsatyuk, P.V., et al. J. Biol. Chem. 284(22):15339-15352(2009)

Additional Info

Human

Alternative Names

IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195

Read more on Supplier website

Applications

ELISA, IF, WB

Hosts

Mouse

Reactivities

Hum

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