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IRP-1 (N707) Peptide

IRP-1 (N707) Peptide

Cat no: BS1761P


Supplier: Bioworld Technology, Inc.
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Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE-BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
Catalogue number: BS1761P
Applications: Block/Neutralize/Inhibit
Swiss prot: P21399
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide IRP-1 (N707). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: ACO1; ACONITASE; EC 4.2.1.3; IREB1; IREBP; IRP1
Additional info: This peptide can be used with studies using BS1761 IRP-1 (N707) pAb.

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