c-Jun N-terminal kinase (JNK) is one of the several main MAP kinase groups identified in mammals. Recent evidences suggest that activation of JNK may play an important role in neuronal apoptosis and other physiological and pathological processes.
Sample Type:
Cell and tissue lysates.
Intended Use:
The kit can be used to screen JNK activity relatively quickly for large numbers of samples.
Test Principle:
The JNK Activity screening BioAssay(TM) kit utilizes an N-terminal c-Jun (1-79) fusion protein bound to glutathion sepharose beads to selectively