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Kallikrein 6, Recombinant, Human, Western Blot Control (Kallikrein-6, Neurosin, Protease M, SP59, Serine Protease 18, Serine Protease 9, ZymeNeurosin, Protease M, SP59, Serine Protease 18, Serine Protease 9, Zyme, KLK6, PRSS18, PRSS9)

Cat no: K0005-09M

Kallikrein 6, Recombinant, Human, Western Blot Control (Kallikrein-6, Neurosin, Protease M, SP59, Serine Protease 18, Serine Protease 9, ZymeNeurosin, Protease M, SP59, Serine Protease 18, Serine Protease 9, Zyme, KLK6, PRSS18, PRSS9)

Kallikreins are a subgroup of serine proteases having diverse physiological functions, from carcinogenesis to novel cancer biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The KLK-6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.\n\nSource: \nRecombinant corresponding to aa15-244 from mature human Kallikrein-6, fused to 6x His-tag at N-terminal, expressed in E. coli.\n\nApplications:\nSuitable for use in Western Blot as a control. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

K0005-09M

Size

10ug

Applications

WB

Form

Supplied as a liquid in 25mM Tris-HCl, pH6.8, 50mM DTT, 1% SDS, 0.1% Bromophenol Blue, 2.5% glycerol.

Purity

Purified (SDS-PAGE)

References

1. Yousef GM, et.al (2003). Clin. Chim. Acta 329 (1-2): 1-8.

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