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KCTD11, Recombinant, Human, aa1-232, His-Tag (BTB/POZ Domain-containing Protein KCTD11, C17orf36, KCASH1, MGC129844, REN, REN/KCTD11)

Cat no: 137099

KCTD11, Recombinant, Human, aa1-232, His-Tag (BTB/POZ Domain-containing Protein KCTD11, C17orf36, KCASH1, MGC129844, REN, REN/KCTD11)

BTB/POZ domain-containing protein KCTD11, is a 232 amino acid regulator of neuronal differentiation that induces growth arrest, apoptosis and the expression of p27, a cyclin-dependent kinase inhibitor. Expressed at highest levels in cerebellum, KCTD11 functions as an antagonist of the Hedgehog pathway and activator of the caspase cascade. \n\nSource: \nRecombinant protein corresponding to human KCTD11, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~28kD (252aa) \n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MLGAMFRAGT PMPPNLNSQG GGHYFIDRDG KAFRHILNFL RLGRLDLPRG YGETALLRAE ADFYQIRPLL DALRELEASQ GTPAPTAALL HADVDVSPRL VHFSARRGPH HYELSSVQVD TFRANLFCTD SECLGALRAR FGVASGDRAE GSPHFHLEWA PRPVELPEVE YGRLGLQPLW TGGPGERREV VGTPSFLEEV LRVALEHGFR LDSVFPDPED LLNSRSLRFV RH\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137099

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.4M urea, 10% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Gallo R., et al. (2002) J Cell Biol. 158:731-740. 2. Di Marcotullio L., et al. (2004) Proc Natl Acad Sci USA. 101:10833-10838.

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Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

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Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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