KDM3A (2E1) Antibody

Cat no: 253093

Supplier: ABBIOTEC

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Description
Additional Information

JMJD1A (Lysine-specific demethylase 3A) is a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and alpha-ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the e, Xenopus/Amphibian,pression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin), therefore,Porcinelays an essential role in spermatogenesis.

Catalogue number:	253093
Reactivities:	Human
Applications:	Immunofluorescence
Size:	0.1 ml
Accession:	Q9Y4C1
Antigen:	Purified recombinant fragment of human KDM3A e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	2E1
Additional info:	Lysine-specific demethylase 3A; JmjC domain-containing histone demethylation protein 2A; Jumonji domain-containing protein 1A; JHDM2A; JMJD1;, JMJD1A; KIAA0742; TSGA; KDM3A