KISS1 Antibody

Cat no: 251265

Supplier: ABBIOTEC

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Description
Additional Information

KISS1 (Metastasis-suppressor KiSS-1) is a metastasis suppressor protein found in malignant melanomas and in some breast cancers. KISS1 regulates events downstream of cell-matri, Xenopus/Amphibian, adhesion,Porcineerhaps involving cytoskeletal reorganization. KISS1 generates a C-terminally amidated peptide,Mouse,etastin, which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of this receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca2+ levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty.

Catalogue number:	251265
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q15726
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within thecenter region of human KISS1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Metastasis-suppressor KiSS-1; Kisspeptin-1; KiSS-1; Metastin; Kisspeptin-14; Kisspeptin-13; Kisspeptin-10; KISS1