KLF4 (1E6) Antibody

Cat no: 253064

Supplier: ABBIOTEC

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Description
Additional Information

KLF4 (Krueppel-like factor 4) is a transcription factor, can act both as activator and as repressor. KLF4 binds the 5'-CACCC-3' core sequence of promoters, and also binds to its own promoter region of its own gene and can activate its own transcription. KLF4 regulates the e, Xenopus/Amphibian,pression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, in preventing their differentiation. POU5F1/OCT4, SO, Xenopus/Amphibian,2,Mouse,YC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differenciated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells e, Xenopus/Amphibian,hibit the morphology and growth properties of ES cells and e, Xenopus/Amphibian,press ES cell marker genes.

Catalogue number:	253064
Reactivities:	Human
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 ml
Accession:	O43474
Antigen:	Purified recombinant fragment of human KLF4 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	1E6
Additional info:	Krueppel-like factor 4; Epithelial zinc finger protein E,Zebrafish/Fish,; Gut-enriched krueppel-like factor; KLF4; E,Zebrafish/Fish,; GKLF