KLF4 Antibody

Cat no: 251435

Supplier: ABBIOTEC

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Description
Additional Information

KLF4 (Krueppel-like factor 4) is a transcription factor, can act both as activator and as repressor. KLF4 binds the 5'-CACCC-3' core sequence of promoters, and also binds to its own promoter region of its own gene and can activate its own transcription. KLF4 regulates the e, Xenopus/Amphibian,pression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, in preventing their differentiation. POU5F1/OCT4, SO, Xenopus/Amphibian,2,Mouse,YC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differenciated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells e, Xenopus/Amphibian,hibit the morphology and growth properties of ES cells and e, Xenopus/Amphibian,press ES cell marker genes.

Catalogue number:	251435
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	O43474
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human KLF4.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	KLF4; Krueppel-like factor 4; Epithelial zinc finger protein E,Zebrafish/Fish,; Gut-enriched krueppel-like factor; E,Zebrafish/Fish,; GKLF